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Some drugs have been withdrawn from the market subsequently to their introduction due to risks for the patients. Usually this has been due to unexpected adverse effects that were not detected during Phase III clinical trials and were only apparent from post-marketing surveillance data from the wider patient community.
A vast mainstream of inhabitants who are on track taking drugs didn't do so to getaway a difficulty in their lives, but basically for the reason that they took the drugs out of inquisitiveness. Prior to they knew it, they were obsessed and their lives fell spaced out.
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Tragic, but that is the truth of drugs. But what did they know about the dangers and conclusion they would ultimately accept when they first started enchanting drugs? Did they make out they would become keen? Did they know how dangerous the drugs were? Did they even think about any of these things?
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List of some Drugs
Thalidomide (1950s-1960s) - withdrawn due to risk of teratogenicity; returned to market as an anti-neoplastic drug under FDA orphan drug rules
Diethylstilbestrol (1970s) - withdrawn due to risk of teratogenicity
phenformin and buformin - withdrawn due to risk of lactic acidosis
ticrynafen (1982) - withdrawn due to risk of hepatitis
methaqualone (1984) - withdrawn due to risk of addiction and overdose.
triazolam (1991) - withdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions
Fen-phen - popular combination of fenfluramine and phentermine; phentermine remains on the market, dexfenfluramine & fenfluramine (1997) later withdrawn
lysergic acid diethylamide (LSD) (1950s-1960s), marketed as a psychiatric cure-all; withdrawn after it became widely used recreationally by hippies
terfenadine (1998) - withdrawn due to risk of cardiac arrhythmias; superseded by fexofenadine
mibefradil (1998) - withdrawn due to dangerous interactions with other drugs
troglitazone (2000) - withdrawn due to risk of hepatotoxicity; superseded by pioglitazone and rosiglitazone
alosetron (2000) - withdrawn due to risk of fatal complications of constipation; reintroduced 2002 on a restricted basis
cisapride (2000s) - withdrawn in many countries due to risk of cardiac arrhythmias
cerivastatin (2001) - withdrawn due to risk of rhabdomyolysis
rapacuronium (2001) - withdrawn in many countries due to risk of fatal bronchospasm
rofecoxib (Bextra) (2004) - withdrawn due to risk of myocardial infarction
